| abstract |
A compound selected from those of formula (I): n n n wherein: n X and Y represent a group selected from hydrogen, halogen, hydroxy, alkoxy, nitro, cyano, alkyl, trihaloalkyl and NR a R b , wherein R a and R b are as defined in the description n R 1 represents hydrogen or alkyl n R 2 represents a group selected from hydrogen, alkyl, —OR″ a , —NR′ a R′ b , -T a -O″ a , —N″ a -T a -NR′ a R′ b , —N″ a —C(O)-T a H, —O—C(O) T a H, T a -NR′ a R′ b , —NR″ a -T a -OR″ a , —NR″ a -T a -CO 2 R″ a and —N″ a —C(O)-T a -NR′ a R′ b , wherein R′ a , R″ a , R′b and T a are as defined in the description n R 3 and R 4 represent hydrogen or alkyl n A represents a group of formula —CH(R 5 )CH(R 6 ), —CH═C(R 7 )—, —C(R 7 )═CH—, —C(O)CH(R 8 ) or —CH(R 8 )—C(O), wherein R 5 , R 6 , R 7 and R 8 are as defined in the description n its isomers, N-oxides, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful in the treatment of cancer. |