| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5767 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-576 |
| filingDate |
2002-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cfa3aad98a18f17f18ac44ab5550c1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fee6bb3a4646d56a6fd2cb97ba21d796
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a05a4c69e4566ad2fab1d9f0a23cd2f |
| publicationDate |
2004-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004265792-A1 |
| titleOfInvention |
Agents for treatment of hcv and methods of use |
| abstract |
An amphipathic helix at the approximate N-terminus of Hepatitis C virus (HCV) nonstructural proteins mediates the association of these proteins with cytoplasmic membranes in infected cells. This association is essential for replication. Thus, assessing the ability of compounds or protocols to disrupt the association of such helices with cytoplasmic membranes permits identification of compounds and protocols which are useful in the treatment of HCV infection. Also useful in the invention are mimics, or function-disrupting ligands, of an amphipathic helix of the nonstructural proteins described herein and antibodies and fragments thereof immunoreactive with said helix. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007232645-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007232627-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007081517-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8338605-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016209173-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7763731-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008261906-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8236950-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2345652-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7655419-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10351604-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7910595-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7915411-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8728793-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009105151-A1 |
| priorityDate |
2001-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |