Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 |
filingDate |
2002-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a16771b2e39b21a89e4846c427610273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31b55ee80d6a795b600288ebb238dba9 |
publicationDate |
2004-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2004259781-A1 |
titleOfInvention |
Anti-tumour agents and methods of identifying anti-tumour agents |
abstract |
The FNIII13 domain of fibronectin and smaller fragments thereof have a tumour cell proliferation inhibitory effect. Compositions are provided comprising fragments of fibronectin having the FNIII 13 domain and fragments thereof. A system comprising cells exposed to fibronectin and caused to proliferate by the presence of tenascin are used as an in vitro method for screening possible anti-tumour agents. Cell-free systems comprising a fibronectin ligand and tenascin are also employed for screening potential anti-tumour or anti-cancer agents. Test compounds are assayed for the ability to disrupt binding of the fibronectin ligand to tenascin. A further cell-free system additionally includes a syndecan molecule. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9234029-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11628222-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010216708-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009297479-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9897612-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11479880-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11299534-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8278419-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11345739-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010051274-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8569227-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9200273-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9200059-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10654913-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10571472-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10040842-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11781138-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9982253-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-028304-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11447539-B2 |
priorityDate |
2001-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |