| abstract |
A sustained release film preparation for local administration to the region of diseases associated with decrease in bone mass, which comprises, as an active ingredient thereof, (11α,13E,15α)-9-oxo-11,15-dihydroxy-16-(3-methoxymethylphenyl)-17,18,19,20-tetranor-5-thiaprost-13-enoic acid methyl ester having the following formula (I) or a non-toxic salt thereof: n n n and a film comprising a biodegradable polymer. The sustained release film preparation which comprises the compound (I) as an active ingredient of the present invention has activity of accelerating bone formation and is useful for treatment of diseases associated with decrease in bone mass. |