http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004248982-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-4926 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-195 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-49 |
| filingDate | 2003-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39774932640b0b63a231b27079221947 |
| publicationDate | 2004-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004248982-A1 |
| titleOfInvention | Use of compounds for the inhibition of proteins and UV protection |
| abstract | The invention treats proteinase-related disorders by interfering with the binding of the metal needed by matrix metalloproteinases, such as PLA-2. The compounds used are known microbial-based chelators of known high solubility. For example, dipicolinic acid has a high affinity to calcium and is soluble in both water and glycerin, as might be expected due to its role in the formation of bacterial endospores. Thus, unlike most chelation agents, the compounds are intended to be permeable enough to cross a vertebrate's cell membrane, a prerequisite for meaningful inhibition of protein-regulated cellular functions such as the inflammatory cascade and accompanying formation of free fatty acids. In addition, because six-ring aromatic chemical structures are inherently durable, it is likely that these compounds will be long-acting, an important attribute because most proteinase-related disorder/diseases are chronic |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006028433-A1 |
| priorityDate | 2003-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.