Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_333fbee44ebb13817b2c2d7fbd22f27b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce33eba5c1cf58da7d563ea223407619 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 |
filingDate |
2004-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_790efa4188e19af2058549dbfd35d361 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbe63bcf21edf451b84118562e0e3f7a |
publicationDate |
2004-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2004248158-A1 |
titleOfInvention |
Differentially expressed genes in large granular lymphocyte leukemia |
abstract |
The subject invention concerns gene sequences and the use thereof as markers for large granular lymphocyte (LGL) leukemia. The gene sequences of the invention are differentially expressed in LGL. Another aspect of the invention pertains to therapeutic compositions directed to gene expression and gene products of differentially expressed genes in LGL. The invention also concerns methods for screening and identifying compositions that may be of therapeutic benefit to patients having LGL leukemia and/or autoimmune disorders. In addition, because a large fraction of patients with T-LGL leukemia also have rheumatoid arthritis, these differentially expressed genes also represent novel targets for the diagnosis, prevention or treatment of rheumatoid arthritis and other autoimmune diseases. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009191217-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019211095-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9528998-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011256636-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008311111-A1 |
priorityDate |
2003-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |