abstract |
An appetite-stimulating agent and a therapeutic agent for anorexia, each comprising, as an active ingredient, a sulfonamide derivative or sulfonic acid ester derivative represented by the following general formula (I): n n n wherein the ring A represents a monocyclic or bicyclic aromatic ring which may be substituted, n the ring B represents a 6-membered unsaturated hydrocarbon ring or a 6-membered unsaturated heterocyclic ring containing one nitrogen atom as a heteroatom, each of which may be substituted, n the ring C represents a 5-membered heterocyclic ring containing one or two nitrogen atoms, which may be substituted, n W represents a single bond or —CH═CH—, n X represents —N(R′)— or an oxygen atom, n Y represents a carbon atom or a nitrogen atom, n Z represents —N(R 2 )- or a nitrogen atom, and n R 1 and R 2 may be identical or different and each represents a hydrogen atom or a lower alkyl group, or a pharmacologically acceptable salt thereof, or a hydrate thereof. |