| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
2002-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aeab358608f5a0a78f44d8d6c729f115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a7df8952f7dbcacde87de5aa96e7d8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83e3655af7283b179cac2941ad7e4be6 |
| publicationDate |
2004-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004241160-A1 |
| titleOfInvention |
Vegfr-1 antibodies to treat breast cancer |
| abstract |
The present invention is directed to methods of inhibiting tumor cells by administering an antagonist which inhibits the VEGF/VEGFR-1 autocrine loop of tumor cells. Additional antagonists can be added to inhibit endothelial paracrine loop by inhibiting other VEGFRs expressed on endothelial cells, particularly VEGFR-2. Examples of antagonists include antibodies and small molecules. A preferred cancer for treatment is breast cancer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2226638-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9650443-B2 |
| priorityDate |
2001-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |