abstract |
The present invention provides a method of increasing the T H1 :T H2 ratio of an immune response, containing the step of supplying to an antigen presenting cell (APC) such as a dendritic cell (DC) or precursor cell, an intracellular activator of APC, such as DC, function. The invention also provides a method of treating a patient with or at risk of allergy comprising the step of supplying an intracellular activator of APC, such as DC, function, or an intracellular inducer of NF κ B, to the patient or to an APC, such as a DC, or precursor cell, of the patient. |