http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004236125-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14727b82242af25381a728ea5833da6d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
| filingDate | 2002-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c413282b211366f7350ef21d289b9f0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87c4efc961ba3651deaac8a7ebb16c83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48da667013b0f84fd71e3f84cdf6348a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a03ceaf538c662a86a9d42d65cd396f4 |
| publicationDate | 2004-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004236125-A1 |
| titleOfInvention | Novel structures and compositions comprising sterols and/or stanols and specific classes of anti-inflammatory agents and use thereof in treating or preventing cardiovascular disease, its underlying conditions including hyperlipidemia and other disorders having inflammation as part of their aetiology or presentation |
| abstract | The present invention provides, in one aspect, novel derivatives comprising sterols and/or stanols and an NSAID selected from salicylic acids and arylalkanoic acids, including salts of these derivatives, and having one or more of the following formulae: n n n wherein R is a sterol or stanol moiety, R 2 is derived from a salicylic acid or an arylalkanoic acid and n=1-5. Also provided are pharmaceutical compositions comprising one or more of these novel derivatives and methods of treating or preventing cardiovascular disease and its underlying conditions including, without limitation, atherosclerosis, hypercholesterolemia, hyperlipidemia, hypertension, thrombosis, coronary artery disease, and for treating and reducing inflammation including coronary plaque inflammation, bacterial-induced inflammation, viral induced inflammation and inflammation associated with acute pain and surgical procedures which comprises administering to an animal, particularly a human, a non-toxic and therapeutically effective amount of one or more of these compounds or a biologically acceptable salt thereof. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006134294-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10086082-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015141390-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7632532-B2 |
| priorityDate | 2002-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 686.