| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-12 |
| filingDate |
2004-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ad9d36edb4f680b61620bf787252772 |
| publicationDate |
2004-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004235879-A1 |
| titleOfInvention |
Method for treatment of chemotherapy-induced diarrhea |
| abstract |
The present invention provides a method for treating diarrhea caused by the interaction of a chemotherapeutic agent with a CFTR protein, which comprises administering sequentially, separately or simultaneously with said chemotherapeutic agent a therapeutically effective amount of a CFTR protein inhibitor to a patient in need of the treatment of such a diarrhea and a method for optimizing time and dosages of a diarrheagenic chemotherapeutic agent in a patient in need thereof, which comprises evaluating the sensitivity of said patients towards said agent through the detection of chloride levels in a biological sample of said patient and selecting a time and dosages of said agent based on the above chloride levels. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006138571-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2371394-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006138571-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009220553-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8263561-B2 |
| priorityDate |
2003-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |