| abstract |
The invention provides isolated nucleic acids molecules, designated 26649, 3259, 57809, 57798, 33358, and 32529 nucleic acid molecules, which encode novel GTPase activating molecules, cadherin molecules, and ankyrin containing family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 26649, 3259, 57809, 57798, 33358, and 32529 nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a 26649, 3259, 57809, 57798, 33358, or 32529 gene has been introduced or disrupted. The invention still further provides isolated 26649, 3259, 57809, 57798, 33358, and 32529 polypeptides, fusion polypeptides, antigenic peptides and anti- 26649, 3259, 57809, 57798, 33358, and 32529 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. |