http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004220125-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 |
| filingDate | 2003-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94ff4303cf958d3c4ef2b67a85a999bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee8f7c846f266ce3ccffa073aa1143ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc33e25389c91c32d1eb80a8b9be5d2c |
| publicationDate | 2004-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004220125-A1 |
| titleOfInvention | Biosynthetic platform for cardioprotective gene expression using immature heart tissue |
| abstract | The present invention is directed toward identification of cardioprotective gene programs in the neonatal heart. Specifically, the newborn (immature) heart or alternatively fetal heart has been recognized as having an increased resistance to pathophysiological forms of stress, e.g. hypoxic stress. The pattern of gene expression in immature heart subject to naturally occurring hemodynamic and hypoxic stress, e.g. that associated with obstructive congenital heart disease, is herein revealed by differential gene profiling; and the induction of a cardioprotective gene pattern, and particularly useful subsets thereof, in the heart chronically adapted to stress is confirmed. Thus, the chronically stressed immature heart provides a novel biosynthetic platform for cardioprotective gene expression, useful as a basis for the development of diagnostic and therapeutic modalities. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011059479-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8440421-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008274491-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7923218-B2 |
| priorityDate | 2003-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 478.