abstract |
The present invention provides a method for locally dispensing a controlled nanoliter volume of a reagent onto a several hundred micron-size region at any desired location on a biological sample, as well as an analytical method for analyzing a biological sample that uses the aforementioned method. A method for dispensing a reagent onto a biological sample, wherein a reagent solution is delivered, by using inkjet technology, to a particular region on a biological sample containing cells or tissues, to make the particular region spotted with the reagent solution. A method for analyzing a biological sample containing cells or tissues, comprising the steps of: dispensing a reagent onto a biological sample for delivering a reagent solution, by using inkjet technology, to a particular region on the biological sample containing cells or tissues, to make the particular region spotted with the reagent solution; subsequently analyzing a target material present in the cells or the tissues by microscopy or mass spectrometry. |