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filingDate 2004-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f2bdf30d88fe987f49a7eba381e0df5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1db4488cae5793f0f417fcb2a3be6781
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0da169951f74f0dbd0e20202b2f3e00
publicationDate 2004-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2004219581-A1
titleOfInvention pH dependent signaling DNA enzymes
abstract Methods for the selection of deoxyribozymes that are active at selected pH ranges are provided. The method comprises detection of a ribonucleotide cleavage event. The detection of catalysis is coupled to the generation of a fluorescent signal. Novel deoxyribozymes which are capable of performing catalysis at pH3, pH4, pH5, pH6 and pH7 were isolated using the methods of the present invention.
priorityDate 2003-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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