| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70503
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-173
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-173
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate |
2002-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_111bb21892267e85f410714b89ed1ac8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dee35b6cf9834af9e45ea324107642a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2fcd8f63bec763354ee2b67970d4d61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d655893f614ed582877c8f63ce9b8cc |
| publicationDate |
2004-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004214881-A1 |
| titleOfInvention |
Method for producing optically active halopropanediol derivative |
| abstract |
The present invention provides a method capable of simply producing optically active halopropanediol derivatives useful as pharmaceutical intermediates from inexpensive raw materials. n Monohalohydroxyacetone derivatives can be produced by reacting propargyl alcohol derivatives available at low cost and a hypohalogenous acid to convert the propargyl alcohol derivatives to di- or tri-halohydroxyacetone derivatives, and then hydrogenating the derivatives in the present of a transition metal catalyst. Also, optically active halopropanediol derivatives can be produced by stereoselectively reducing the halohydroxyacetone derivatives with an enzyme source having the ability to stereoselectively reduce the carbonyl groups of the halohydroxyacetone derivatives. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113528558-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112680366-A |
| priorityDate |
2001-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |