http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004171532-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c29ebbacb306f9b12e38ffad61728746 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate | 2004-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcb6387c98592cdf6966e1cebde8b9e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21158a02f006426dbf92e1eed891513c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35a862296be04e0fea0df6eaa897da8b |
| publicationDate | 2004-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004171532-A1 |
| titleOfInvention | Method and compositions for administering taxanes orally to human patients |
| abstract | Taxane antineoplastic agents which have heretofore exhibited poor or non-existent oral bioavailability are administered orally to human patients suffering from taxane-responsive disease conditions and made sufficiently bioavailable to achieve therapeutic blood levels. In a preferred embodiment, the taxane, preferably paclitaxel, is co-administered to the patient with an oral cyclosporin enhancing agent, preferably cyclosporin A. By one preferred method, a dose of oral enhancer is administered about 0.5-72 hours before the taxane and a second dose of the enhancer and administered immediately before, together with or immediately after the taxane. A method of treating human patients suffering from taxane-responsive disease conditions is also provided, as well as a method for providing such treatment while preventing or reducing hypersensitivity and allergic reactions without the need for pre-medication. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7691812-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8357660-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006094646-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8703715-B2 |
| priorityDate | 1995-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.