| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate |
2003-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4c1f7e8cc4cbc0e56831f3b11b8d6f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4818d031d89f0407f61e5a7d5d300035
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff49b85572edcf641913d18812987bee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ae961ccda206682bbbd0591ca169c96 |
| publicationDate |
2004-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004161781-A1 |
| titleOfInvention |
Compositions and methods for identifying thymidylate synthase modulators |
| abstract |
The present invention provides compositions and methods for screening of compounds that decrease the activity of thymidylate synthase either directly or indirectly. The composition of the invention comprises a DNA construct comprising from the 5′ to the 3′ direction, a TBE cassette comprising one or more copies, in forward or reverse orientation, of TBE1 and TBE2, and a reporter gene operably linked to a promoter and optionally a selectable marker. The method of the invention comprises growing cells comprising the construct of the invention in the presence or absence of a test compound such that a test compound which decreases the activity of |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007010477-A1 |
| priorityDate |
2002-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |