Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2c2459d9831616925869af1a2de323e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2004-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f360a51b871a0fa6732174533f73cb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa3bbdc464cb1c4969610825c5dd2547 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e79c4fec9669c1a8575edf5efc5605c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c895d5d6feeddc4c9fe62ad62a6af53b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e730fbc0a9bc9493a3f31cf589983a25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cad11919255b091a8928cbf1f0924e1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6904f3a12ed509aa7a17f7e1b8efcfa5 |
publicationDate |
2004-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2004142374-A1 |
titleOfInvention |
PAAD domain-containing polypeptides, encoding nucleic acids, and methods of use |
abstract |
The invention provides isolated nucleic acid molecules encoding PAAD-domain containing polypeptides and functional fragments thereof, including fragments containing PAAD domains, NB-ARC domains and LRR domains, encoded polypeptides, and antibodies. Also provided are methods of identifying polypeptides and agents that associate with a PAAD-domain containing polypeptide or fragment thereof, or that alter an association of a PAAD domain-containing polypeptides. Further provided are methods of identifying agents that modulate PAAD domain-mediated inhibition of NFkB activity, or modulate an activity of an NB-ARC domain of a PAAD domain-containing polypeptide. Also provided are methods of modulating NFkB transcriptional activity in a cell, and methods of altering expression of a PAAD domain-containing polypeptide in a cell. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007148164-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8618252-B2 |
priorityDate |
2000-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |