| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-382
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-366
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-045 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-366
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-382
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 |
| filingDate |
2003-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aeea8e57cd63e30d075f9ed04634d275 |
| publicationDate |
2004-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004138258-A1 |
| titleOfInvention |
Inhibitors of 11beta-hydroxysteroid dehydrogenase and uses therefor |
| abstract |
The present invention identifies natural and man-made inhibitors of the 11β-hydroxysteroid dehydrogenase enzymes that modulate glucocorticoid bioactivity in vivo by catalyzing either the formation of cortisol by reduction of cortisone, or the removal of cortisol by oxidation to cortisone. This mode of modulating glucocorticoid bioactivity in vivo is significant for inflammatory and allergic conditions, cancer, and several metabolic syndromes. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006159622-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006148725-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003148987-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005020550-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019195744-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010048778-A1 |
| priorityDate |
2002-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |