http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004110780-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 2003-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87b5dbce952b03a8b0bad726978adbac |
| publicationDate | 2004-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004110780-A1 |
| titleOfInvention | Pyrimidine derivatives useful in the treatment of insulin resistance and hyperglycemia |
| abstract | This invention provides compounds of Formula I having the structure: n n n wherein: n B is alkyl of 1-4 carbons or alkoxy of 1-4 carbons; n R 1 is aryl or Het optionally substituted with R 6 ; n R 2 and R 3 are each independently, alkyl of 1-4 carbons, CF 3 , aryl or Het substituted with R 6 , or R 2 and R 3 are combined to form a cycloalkyl or heterocyclic ring optionally substituted with alkyl, benzyl, or acyl; n R 4 , and R 5 are each independently, hydrogen, halogen, alkyl of 1-4 carbons, CO 2 R 7 , SO 2 NHR 7 , CONHR 7 , CN, NO 2 or CF 3 ; n R 6 is hydrogen, halogen, NO 2 , alkyl of 1-4 carbons, alkoxy of 1-4 carbons, alkylcarbonyloxy of 2-7 carbon atoms, alkylcarbonyl of 2-7 carbon atoms, CF 3 , or COOH; and n R 7 is hydrogen, alkyl of 1-4 carbons, or alkylaryl where aryl group is substituted with n R 6 ; or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4775767-B2 |
| priorityDate | 2002-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 422.