| abstract |
An agent for preventing or treating portal hypertension comprising a compound represented by the general formula (I): n n n wherein R 1 represents a group capable of forming an anion, etc.; X represents a bond or a spacer; n is an integer of 1 or 2; ring A is benzene ring which may be further substituted; R 2 represents a group capable of forming an anion, etc.; and R 3 represents a hydrocarbon group which may bonded via a hetero atom, and may be substituted, a salt thereof or a prodrug thereof, is provided. This agent has sufficiently excellent properties as medicine, since it has excellent prophylactic and therapeutic effects on portal hypertension without any side effect, etc. |