abstract |
Compounds of formula (I): n n n wherein: n R 1 represents a group selected from hydrogen, alkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, alkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl, heterocycloalkoxycarbonyl, alkylsulfonyl, arylsulfonyl, arylalkylsulfonyl and phosphonic, n R 2 represents an oxygen atom or a sulphur atom, n R 3 represents a hydrogen atom or an alkyl, cycloalkyl or arylalkyl group, n X represents a linear or branched (C 1 -C 6 )alkylene group, n R 4 represents a group selected from amino optionally substituted by one or two groups, a group of formula —N(R 3 )—X 1 —OR 5 wherein R 3 , X 1 and R 5 are as defined in the description, a group of formula —N(R 3 )—X 1 -NR 6 R 7 wherein R 3 , X 1 , R 6 and R 7 are as defined in the description, hydroxy, alkoxy, aryloxy, a group of formula —O—X 1 —OR 5 wherein R 5 and X 1 are as defined in the description, and a group of formula —O—X 1 —NR 6 R 7 wherein R 6 , R 7 and X 1 are as defined in the description, n their isomers, and also addition salts thereof with a pharmaceutically acceptable acid or base. |