Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-3094 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-2835 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3847 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3687 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3691 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-365 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-30 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-28 |
filingDate |
2003-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cd23dc36c6051a7715d8265066b9474 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e5ae98e1f871b692e1873dbfafa0d38 |
publicationDate |
2004-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2004098135-A1 |
titleOfInvention |
Bone xenografts |
abstract |
The invention provides an article of manufacture comprising a substantially non-immunogenic bone xenograft (X) for implantation into a defect (D) located in a bone portion ( 10 ) of a human. The invention further provides methods for preparing a bone xenograft (X) by removing at least a portion of bone from a non-human animal to provide a xenograft (X); washing the xenograft (X) in saline and alcohol; and subjecting the xenograft (X) to at least one of the treatments including exposure to ultraviolet radiation, immersion in alcohol, ozonic, and freeze/thaw cycling. In addition to or in lieu of the above treatments, the methods include a cellular disruption treatment, and digestion of the carbohydrate moieties of the xenograft (X) with a glycosidase followed by treatment for sialylation. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8753406-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7749555-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007173950-A1 |
priorityDate |
1998-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |