http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004095140-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-4633 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-465 |
| filingDate | 2003-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83f5f489c1e2cbb9054ecf58ddf1b319 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8128e5a1959f2a2fd7a9c97d86da477d |
| publicationDate | 2004-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004095140-A1 |
| titleOfInvention | Phase sensitively-detected reduced dimensionality nuclear magnetic resonance spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins |
| abstract | The present invention discloses eleven reduced dimensionality (RD) triple resonance nuclear magnetic resonance (NMR) experiments for measuring chemical shift values of certain nuclei in a protein molecule, where the chemical shift values encoded in a peak pair of an NMR spectrum are detected in a phase sensitive manner. The RD 3D HA , CA ,(CO),N,HN NMR and RD 3D H , C ,(C-TOCSY-CO),N,HN NMR experiments are designed to yield “sequential” connectivities, while the RD 3D H α/β , C α/β ,CO,HA NMR and RD 3D H α/β , C α/β ,N,HN NMR experiments provide “intraresidue” connectivities. The RD 3D H , C ,C,H-COSY NMR, RD 3D H , C ,C,H-TOCSY NMR, and RD 2D H , C ,C,H-COSY NMR experiments allow one to obtain assignments for aliphatic and aromatic side chain chemical shifts, while the RD 2D HB , CB ,(CG,CD),HD NMR experiment provide information for the aromatic side chain chemical shifts. In addition, methods of conducting suites of RD triple resonance NMR experiments for high-throughput resonance assignment of proteins and determination of secondary structure elements are disclosed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7920972-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009009166-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7141432-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004061497-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005244929-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7365539-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005114038-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7880468-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6831459-B2 |
| priorityDate | 2002-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 164.