| abstract |
Methods and apparatuses for the high-energy desorption/ionization of various compositions are disclosed. The methods and apparatuses of the invention generally utilize structured substrates, such as micro- and nano-structured films, optionally in combination with one or more surface coatings, to provide enhanced desorption of analytes. Such enhanced desorption is particularly useful in fields of analysis such as mass spectroscopy which use laser desorption of the substrate. |