| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2002-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bcb17b0c84303c8017a2fe8c78d6552 |
| publicationDate |
2004-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004082075-A1 |
| titleOfInvention |
Multi-step NMR for the identification and evaluation of biomolecule-compound interactions |
| abstract |
Provided are methods of evaluating binding or a compound to a biomolecule. The methods utilize 1D NMR of the compound and 1D or 2D NMR of the biomolecule-compound mixture, along with 2D HSQC or TROSY methodology if a biomolecule-compound complex is formed. These methods are useful for evaluating biomolecule binding with more than one compound, e.g., a library of compounds, either individually or in mixtures. The methods are also useful for NMR evaluation of the effects of competition between a compound and a known binder such as an inhibitor of biomolecule activity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7202664-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108108892-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008125977-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023012203-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005110495-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009151696-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008127388-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009151696-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4130727-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11415533-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10866295-B2 |
| priorityDate |
2002-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |