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filingDate 2002-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd6ea0a9e18ac5f857c8931e29a90559
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publicationDate 2004-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2004072912-A1
titleOfInvention Process for the manufacture of pharmaceutical tablets contaning paroxetine hydrochloride anhydrate
abstract Pharmaceutical tablets containing crystalline paroxetine hydrochloride anhydrate are prepared using a process comprising an initial wet granulation process in which an aqueous granulation liquid is added to a mixture of said anhydrate an excipients under high-shear conditions and the thus obtained wet granules are dried using a fluidized bed technique to obtain a water activity within a specified range, after which the dried granules after addition of further adjuvants are compressed into stable tablets each having an identical composition.
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