http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004072371-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0459 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0406 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 |
| filingDate | 2003-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bd7a910ae3dd23ae931e96e512c67cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62226ce6c115a2196837bd604bcb5358 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69fbf0138d72923a4b9a7fc94a6e7abd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee5ee763348f4b453f5794c7614c2d5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dbce10fd67a5222c685bf4604758ad6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d008e31effb785e6fa33cb43741d3392 |
| publicationDate | 2004-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004072371-A1 |
| titleOfInvention | Compositions for labeling beta-amyloid plaques and neurofibrillary tangles |
| abstract | Compositions useful for labeling β-amyloid plaques and neurofibrillary tangles are provided. The compositions comprises compounds of formula (I): n n n wherein R 1 is selected from the group consisting of —C(O)-alkyl, —C(O)-alkylenyl-R 4 , —C(O)O-alkyl, —C(O)O-alkylenyl-R 4 , —C═C(CN) 2 -alkyl, —C═C(CN) 2 -alkylenyl-R 4 , n n n wherein R 4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R 5 is a radical selected from the group consisting of —NH 2 , —OH, —SH, —NH-alkyl, —NHR 4 , —NH-alkylenyl-R 4 , —O-alkyl, —O-alkylenyl-R 4 , —S-alkyl, and —S-alkylenyl-R 4 ; R 6 is a radical selected from the group consisting of —CN, —COOH, —C(O)O-alkyl, —C(O)O-alkylenyl-R 4 , —C(O)-alkyl, —C(O)-alkylenyl-R 4 , —C(O)-halogen, —C(O)NH-alkyl, —C(O)NH-alkylenyl-R 4 and —C(O)NH 2 ; R 7 is a radical selected from the group consisting of O, NH, and S; and R 8 is N, O or S; and R 2 is selected from the group consisting of alkyl and alkylenyl-R 10 and R 3 is alkylenyl-R 10 , wherein R 10 is selected from the group consisting of —OH, —OTs, halogen, spiperone, spiperone ketal, and spiperone-3-yl, or R 2 and R 3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkyl-R 10 , carbonyl, spiperone, spiperone ketal and spiperone-3-yl, and further wherein one or more of the hydrogen, halogen or carbon atoms are optionally replaced with a radiolabel. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10377701-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012321560-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10626083-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011286932-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2860169-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9764047-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10512699-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9839699-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010118706-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018089491-A1 |
| priorityDate | 1998-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 232.