http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004072222-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4713 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate | 2001-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4555f9a345961df791894695209d3273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cc95d067372bee0ae936851e1015457 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b1f1d7442263497d426f2d24a644ddf |
| publicationDate | 2004-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004072222-A1 |
| titleOfInvention | Peptide analogues of myelin basic protein epitopes in the treatment of experimental autoimmune encephalomyelitis (eae) and multiple sclerosis (ms) |
| abstract | This invention relates to novel linear and cyclic peptide analogues of Myclin Basic Protein epitopes (from guinea pig MBP 72-85 and human MBP 87-99 ) and their conjugates with mannan and/or KLH useful in the treatment of Experimental Autoimmune Encephalomyclitis (EAE) and Multiple Sclerosis (MS). For the first time cyclic analogues of MBP epitopes have been synthesized and shown to prevent the development of EAE. There is gathering evidence that analogues of disease-associated epitopes can be conjugated to mannan and/or KLH and actively generate antigen specific regulatory CD4/CD8 T cells and Th1/Th2 cytokines. |
| priorityDate | 2001-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 394.