| abstract |
A transdermal therapeutic system embodied as a matrix or reservoir system is characterized by n a content of at least one basic- or neutral-reacting pharmaceutical active agent n a content of a pressure-sensitive adhesive polymer which possesses as part of its chain acrylic acid or methacrylic acid units,,the content of the carboxyl groups, relative to the-mean polymer mass, being 0.5 to 10.0% (m/m) and the carboxyl groups being present stoichiometrically at 5 to 110%, preferably 10 to 50%, in form of alkali salts or alkaline earth salts. |