abstract |
This invention relates to benzopyran derivatives of the formula (I) wherein, R 1 and R 2 represent each independently a C 1-6 alkyl group, etc, R 3 represents a hydroxyl group, etc, R 4 represents a hydrogen atom, etc, R 6 represents a hydrogen atom, R 7 represents a hydrogen atom, etc, X is absent, or represents C═O, etc, R 8 represents a hydrogen atom, a C 1-6 alkyl group, etc, R 9 represents a hydrogen atom or a nitro group, when R 9 represents a nitro group, Y represents a C 4-8 alkylene group, —(CH 2 ) m —CR 11 R 12 —(CH 2 ) n — or —(CH 2 ) o —O—(CH 2 ) p —, R 5 represents a hydrogen atom, an amino group, a C 1-6 alkoxy group, a C 1-6 alkylthio group, a C 1-6 alkylamino group, a C 1-6 alkoxycarbonylamino group, etc, or pharmaceutically acceptable salts thereof. These compounds are useful as an antiarrhythmic agent. |