| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 |
| filingDate |
2001-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02d63f69382e4c20031ce9ddb4c2c545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e77952c257de727bbd8e8723160e6ba7 |
| publicationDate |
2004-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004067236-A1 |
| titleOfInvention |
Immunogenic compositions comprising liver stage malarial antigens |
| abstract |
A vaccine composition comprising a Th1-inducing adjuvant in combination with a protecting Liver Stage Antigen or immunological fragment thereof of a human malaria parasite, especially Plasmodium falciparum , with the proviso that when the immunological fragment is an immunological fragment of LSA-3 the Th1-inducing adjuvant is not Montanide. In one preferred aspect the Th1-inducing adjuvant comprises QS21, De-O-acylated monophosphoryl lipid A (3D-MPL) and an oil in water emulsion wherein the oil in water emulsion has the following composition: a metabolisible oil, such a squalene, alpha tocopherol and tween 80. In a further preferred aspect the protecting Liver Stage Antigen is Liver Stage Antigen 3 (LSA-3) or an immunological fragment thereof. A multivalent vaccine composition is also provided comprising the vaccine composition of the invention and in addition at least one other protecting antigen or an immunological fragment thereof, of a malaria parasite. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7087231-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9592282-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7438917-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010062028-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7563440-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6949627-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002041882-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7071296-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9364525-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006182769-A1 |
| priorityDate |
2000-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |