http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004053848-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
filingDate | 2001-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e798c9a2c1e8b19989d17c42ae9451cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35cff44499631dd94d903093ccdfa484 |
publicationDate | 2004-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2004053848-A1 |
titleOfInvention | Antibodies specific for methylated lysines in histones |
abstract | The present invention related to the generation of methyllysine-specific histone antibodies. In particular, the H3 lysine 4 methylation specific antibody (Methyl(K4)H3) binds to histone H3 methylated at lysine 4. Methylation of lysine 4 (K4) on histone H3 has been associated with transcriptionally active regions of chromatin. A second antibody, H3 lysine 9 methylation specific antibody (Methyl(K9)H3) specifically binds to histone H3 methylated at lysine 9. Methylation of lysine 9 (K9) on histone H3 has been associated with gene silencing. These antibodies are useful in identifying regions of heterochromatin and euchromatin and serving as diagnostic and screening tools. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007196843-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286611-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004241756-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7074578-B2 |
priorityDate | 2001-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 459.