http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004048865-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2003-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_707ae19aa1a9ffe8c428f6a673982eee |
| publicationDate | 2004-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004048865-A1 |
| titleOfInvention | Antagonists of chemokine receptors |
| abstract | Compounds are provided which are antagonists of chemokine receptor activity. n The compounds thereof have the structure n n n including enantiomers, diastereomers, tautomers, pharmaceutically acceptable salts and solvates thereof wherein: n A, B, D, E, X and Y are selected from N or C, J and K are C, and at least one of A, B, D, E, X and Y is N; n L is selected from O, NH and S, wherein L may be connected to any one of A, B, D, E, J, X, K or Y; n M is CH or N; n P is a bond or C═O, wherein P is connected to any one of J, X, K or Y; n Z is —(CFG)R 2 where F is O, H 2 , alkyl or substituted alkyl and G is O or N or none; n n is 0-4; n R 1 is selected from halogen, —CN, —CF 3 , substituted alkyl, aryl and heteroaryl; n R 2 is a heterocyclyl containing at least one N; n R 3 is selected from halogen, cyano, alkyl, substituted alkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl, wherein R 3 is connected to any one of A, B, D and E; n R 4 and R 5 are H; n or R 4 and R 5 may be taken together with the atoms to which they are attached to form a ring; and n R 10 is selected from H, alkyl, substituted alkyl, alkenyl, substituted alkenyl; n or E and R 10 may be taken together with the atoms to which they are attached to form a heteroaryl or heterocycloalkyl ring. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9278098-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7790884-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009131666-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2000469-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010105690-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8987321-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008146544-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2000469-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007111227-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8481580-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8871764-B2 |
| priorityDate | 2002-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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