| abstract |
Disclosed are novel compounds of the formula n n n wherein R 1 is benzimidazolone derivative, M 1 and M 2 are optionally substituted carbon or nitrogen, R 2 includes optionally substituted aryl or heteroaryl, and the remaining variables are as defined in the specification. n Also disclosed are pharmaceutical compositions comprising the compounds of formula I. n Also disclosed are methods of treating various diseases or conditions, such as, for example, allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of Formula I. n Also disclosed are methods of treating various diseases or conditions, such as, for example, allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of formula I in combination with a H 1 receptor antagonist. |