http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004048258-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b215416da30a611c891885f5111ae10 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a45c54cff65a793b2f8f3ef419123e19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1d895dfab7ac99bf51adbdfb1afea55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7264b59e0d0300868cc79bb2e0077663 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c784408df950d43bfccd277aea25fe6d |
publicationDate | 2004-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2004048258-A1 |
titleOfInvention | Multiple-gene diagnostic probes and assay kits and method for the assessment of multiple markers for breast cancer prognosis |
abstract | The problem of inadequate broad-range prognostic factors for breast cancer is solved by providing a multi-gene probe for a single-step determination of disease outcome. The 5-genes chosen (HER2, Topo IIα, NM23-H1, CK19 and MMP9) are known to show altered expression in different breast tumors. The altered expression of any one of them has a similar prognostic significance, with respect to disease-free survival or overall survival. The multi-gene probe is labeled and used to screen a tumor specimen. The signal generated after the assay provides information that has prognostic significance. Since five prognostic markers are simultaneously assessed, a wider variety of breast cancers are covered and disease outcome prediction is improved in a wider population. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9593374-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004063325-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004063325-A3 |
priorityDate | 2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.