http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004038875-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2001-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4d117f73670ecb31ec6ab0b41bb4ab1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f63571a58d155b3729bb92e31da589aa |
| publicationDate | 2004-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004038875-A1 |
| titleOfInvention | Alpha 7nicotinic receptor screening assays |
| abstract | The present invention relates to screening assays for functional analogues and antagonists of a polypeptide fragment of acetylcholinesterase (AChE), which is believed to exhibit activity corresponding to non-enzymatic function of AchE in the brain. These assays stem from linkage of such non-enzymatic activity with a target site on the homomeric alpha 7 nicotinic receptor. Antagonists thus identified which are capable of formulation for passage through the blood-brain barrier may be advantageous therapeutic agents for the treatment of a number of neurodegenerative diseases, in particular Alzheimer's Disease, Parkinson's Disease and Motor Neuron Disease. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019511701-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10345292-B2 |
| priorityDate | 2000-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 179.