| abstract |
The present invention features a coating consisting of a functionalized polymeric surface coating comprising reactive entities. These entities could consist of amino-, hydroxyl; epoxy- or other covalently linked in a polymer network of polyurea and polyurethane to provide a surface coating. This functionalized coating is applied to surfaces of a non-woven material composed of fibers. One embodiment of present invention is application to fibers at a level of 0.01 to 1 micromole/cm 2 amine without poragens to be utilized for peptide and combinational chemistry synthesis. Furthermore, the coating can be applied to fiber at a high level with a crinkly fiber coating abased on the use of a poragen, thus creating a matrix having a higher loading on higher surface area for synthesis and other applications. These embodiments may be applied to various fields and technologies, e.g., proteomics, genomics, combinatorial chemistry, and chromatography. |