| abstract |
Compounds of formula I, n n n wherein n R 1 represents C 1-4 alkoxy optionally substituted by one or more fluorine atoms; n R 2 represents an aryl group or a heteroaryl group, optionally substituted by C 1-4 alkyl or SO 2 NH 2 ; n R 3 represents a 4-, 5-, 6-, or 7-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring system as, a whole being optionally substituted; n X represents CH or N; and n L is absent, or represents a cyclic group of formula Ia, n n n or represents a chain of formula Ib, n n n and pharmaceutically acceptable salts thereof, are useful in the treatment of a variety of disorders including benign prostatic hyperplasia. |