http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004033242-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7007 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 |
| filingDate | 2002-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c375c2cbeda01ccaee952b013168c7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_130fd3e4d2a4e5f257332eae943e07ad |
| publicationDate | 2004-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004033242-A1 |
| titleOfInvention | Two dimensional polymer that generates nitric oxide |
| abstract | A polymeric composition that generates nitric oxide and a process for rendering the surface of a substrate nonthrombogenic by applying a coating of the polymeric composition to the substrate are disclosed. The composition comprises: (1) a crosslinked chemical combination of (i) a polymer having amino group-containing side chains along a backbone forming the polymer, and (ii) a crosslinking agent containing functional groups capable of reacting with the amino groups; and (2) a plurality of nitric oxide generating functional groups associated with the crosslinked chemical combination. Once exposed to a physiological environment, the coating generates nitric oxide thereby inhibiting platelet aggregation. In one embodiment, the nitric oxide generating functional groups are provided by a nitrated compound (e.g., nitrocellulose) imbedded in the polymeric composition. In another embodiment, the nitric oxide generating functional groups comprise N 2 O 2 − groups covalently bonded to amino groups on the polymer. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7928079-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919542-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011104240-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011106000-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005043506-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009153275-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8334342-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009124722-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007274874-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011124807-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008306012-A1 |
| priorityDate | 2002-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 146.