| abstract |
The present invention relates to fatty acid analogues of general formula (I): R 1 -[x i -CH 2 ] n —COOR 2 , wherein is: a C 1 -C 24 alkene with one or more double bonds and/or with one or more triple bonds; and/or a C 1 -C 24 alkyne, and/or a C 1 -C 24 alkyl, or an alkyl substituted in one or several positions with one or more compounds selected from the group comprising fluoride, chloride, hydroxy, C 1 -C 4 alkoxy, C 1 -C 4 alkylthio, C 2 -C 5 acyloxy or C 1 -C 4 alkyl, and wherein R 2 represents hydrogen or C 1 -C 4 alkyl, and wherein is an integer from 1 to 12, and wherein i is an odd number and indicates the position relative to COOR 2 , and wherein X i independent of each other are selected from the group comprising O, S, SO, SO 2 , Se and CH 2 , and with the proviso that at least one of the X i is not CH 2 , which can be used for the treatment and/or prevention of primary and secondary metastatic neoplasms. |