abstract |
The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula: n n n wherein each X is independently selected from: n i) —C(W) 2 —; n ii) —C(O)—; n iii) —NR 2 —; n iv) —S—; n v) —S(O)—; n vi) —S(O) 2 —; n vii) two units, one from each adjacent X unit, can be taken together to form a substituted or unsubstituted double bond having the formula —CW═CW—; wherein each W is hydrogen of a unit having the formula —(L 2 ) j —R 2 , the index j is 0 or 1; n R is a carbocyclic or heterocyclic aryl ring; n R 1 is a cysteine trap; n each R 2 is independently a suitable substituent; and n L, L 1 , and L 2 are linking units. |