Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
2002-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00d69233f0f967e7b63215a4dfdec087 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bccacb655d3754b37a2eca755941f03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5633554e0d1709fe07d163ca69d7be9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17bd72769ddd2c6f41b27df00bafe526 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60a45be0a8ba50864405072dd358b99c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40d225c0ccbd8b98bb86aa8ecc33c422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d348a93eb216c9f4db613d7ed7eb6dfc |
publicationDate |
2004-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2004009568-A1 |
titleOfInvention |
Catalytic domains of the human hepatocyte growth factor receptor tyrosine kinase, and materials and methods for identification of inhibitors thereof |
abstract |
The identification, isolation, purification, and characterization of the catalytic domain of the human hepatocyte growth factor receptor kinase (hHGFR) are described. A crystal structure of the hHGFR kinase domain is reported herein. This structure provides a three-dimensional description of the binding site of the hHGFR for structure-based design of small molecule inhibitors thereof as therapeutic agents. The kinase domain of human HGFR and its associated crystal structure is described for use in the discovery, identification and characeterization of modulators of human HGFR. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10302656-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007043509-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2011352231-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2659267-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9372195-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007219767-A1 |
priorityDate |
2001-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |