| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-525 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6845
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24 |
| filingDate |
2003-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f80a8988f2f1720d9cd21fdb7d8bc955
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90d09c0d3e0ea1bba8d26eb8e0e8e375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6445aa3b520de4488b8e77e0e046ea67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e1ef88f66b64b1bffa0ffa785a46ee9 |
| publicationDate |
2004-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004009166-A1 |
| titleOfInvention |
Single chain antigen-binding polypeptides for polymer conjugation |
| abstract |
The present invention relates to monovalent and multivalent single-chain antigen-binding polypeptides with site-specific modifications. The provided polypeptides are capable of being covalently linked or conjugated to polyalkylene oxides at the modified sites. The resulting conjugates retain antigen binding properties and exhibit prolonged circulating time and reduced antigenicity relative to unconjugated single chain antigen binding polypeptides. Methods and compositions for making and using the single chain antigen-binding polypeptides with site-specific modifications are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9090689-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11730822-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11608517-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9605064-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8986693-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006125229-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8906373-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286066-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9512216-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2173380-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006125229-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8808700-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008008713-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8715664-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007071747-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018013563-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3484488-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2173380-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9028822-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11229708-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11103593-B2 |
| priorityDate |
1997-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |