http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004001837-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 |
| filingDate | 1998-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97bdbf34a3ea7be7a1d1235a2dc27231 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_141c4c4ce869156585e532620d289e11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01805f4e137fa956953a19ec2e4c0324 |
| publicationDate | 2004-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2004001837-A1 |
| titleOfInvention | Betulinol derivatives |
| abstract | The present invention is directed to betulinol derivatives and betulinol-antibody conjugates having the formulae: n n n and n HO-antibody-spacer-(A 2 ) n n wherein n A 1 is a moiety having the formula: n n n A 2 is a moiety having the formula: n n n n is an integer from 1 to 100; n X and Y 1 are each independently selected from the group consisting of a hydroxy group, an alkoxy group, an alkanoyloxy group, and a-peptide-NHNH—C(O)-antibody-OH moiety; n Y 2 is selected from the group consisting of a hydroxy group, an alkoxy group, and an alkanoyloxy group; and n HO-antibody-H is an antibody n and, in particular, betulinol dimethyl ether. Methods for making and using these derivatives and conjugates, as well as a method for making and using betulonic aldehyde, are also disclosed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008070347-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008070347-A3 |
| priorityDate | 1997-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 386.