| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-215 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-215 |
| filingDate |
2003-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ca5a3cac7c8c5bce51e54dccd1f58f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a2b3f671ac2217b8381a6a7aec050c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6d73f6a9ec9408d9cedf3623f60516f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03657b8b3e45e1cf05557ae738aabe93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd5224d6977055dc2b1a351e9548dae2 |
| publicationDate |
2003-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003232779-A1 |
| titleOfInvention |
Determination and uses of the atomic structures of ribosomes and ribosomal subunits and their ligand complexes |
| abstract |
The present invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as the crystals produced by such methods. The x-ray diffraction patterns of the crystals provided by the present invention are of sufficiently high resolution for determining the three-dimensional structure of ribosomes and ribosomal subunits, for identifying ligand binding sites on ribosomes and ribosomal subunits, and for molecular modeling of ligands which interact with ribosomes and ribosomal subunits. The present invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties. Thus, the methods of the present invention may be used to produce ligands which are designed to kill or inhibit any specific target organism(s). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8912150-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7666849-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8470990-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016120868-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007118296-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005272681-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8374794-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8428884-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003153002-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6952650-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010204253-A1 |
| priorityDate |
2000-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |