| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-19 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2003-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9791dc672011e65a541164694b6156a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f11c07386864d8a4c8ea091d16ce67b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b99de80b2f751d18c8d92506d1f6eb90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fc4f35f61eed1722857417a2ce971d9 |
| publicationDate |
2003-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003232416-A1 |
| titleOfInvention |
Synthesis of synthons for the manufacture of bioactive compounds |
| abstract |
The present invention is based on the discovery that 2-deoxyribose-5-phosphate aldolase (DERA, EC 4.1.2.4) and variants therefor can be used to catalyze sequential asymmetric aldol reactions between a wide variety of donor and acceptor aldehydes. The reaction products typically contain at least two new stereogenic centers and can be produced in enantiomerically pure form. As such, DERA catalyzed asymmetric aldol chemistry can be exploited to produce synthons for the synthesis of a variety of bioactive molecules. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7414119-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005118794-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005153407-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8148324-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005118794-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008289056-A1 |
| priorityDate |
2002-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |