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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
filingDate 2002-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76be02f3cfb94ca2873e855e7b5205c6
publicationDate 2003-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2003228642-A1
titleOfInvention Crohn's disease treatment and efficacy prediction methods
abstract A method for determining a potential efficacy of an administration of immunotherapy for treating Crohn's disease includes screening for a presence of Mycobacterium avium ss. paratuberculosis (MAP) in a serum of a patient. In another embodiment, Crohn's disease is treated by screening for a presence of MAP in a serum of a patient and avoiding a use of immunotherapy as a primary treatment if the patient screens serologically positive for MAP. Preferably, the patient is treated with a regimen of antibiotics to eradicate a presence of MAP. Then, if necessary, immunotherapy may be undertaken, preferably following a regimen of probiotics.
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