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publicationDate 2003-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2003225095-A1
titleOfInvention Method of affecting sleep and sleep-related behaviors
abstract A method of affecting sleep and sleep-related behaviors of a mammal having a diurnal rhythm, by reducing the basal activity of the hypothalamus-pituitary-adrenal axis by administering an effective amount of a sensory regimen is disclosed. Such reduction may be accomplished by reducing at least one of the following: n a. the average total daily amount of adrenocortical hormone; or n b. the average total daily amount adrenocortical hormone minus the integrative measure of morning peak adrenocortical hormone. n Preferably, such reduction also includes reducing at least one of the following: n c. the level of adrenocortical hormone 4 hours to 8 hours after waking; n d. the level of adrenocortical hormone in the period of time preceding bedtime; or n e. the level of adrenocortical hormone below the onset of sleep threshold.
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